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In this hour-long lecture, Professor Roger Kamm discusses the development of complex in vitro systems for studying neurovascular function in both healthy and diseased states. Learn about the rising challenge of neurodegenerative diseases in our aging population and how innovative microfluidic platforms are being created to test drug delivery across the blood-brain barrier. Discover how these advanced models recapitulate in vivo morphology and function, enabling pharmaceutical companies to screen new therapeutics for neurological and neurodegenerative diseases. Professor Kamm, a member of the National Academies of Medicine and Engineering, shares his expertise at the intersection of biology and mechanics, highlighting his work in developing microfluidic technologies for modeling organ function with a focus on vascularization, cancer, and neurological disease. This presentation is sponsored by the Center for Physical Genomics and Engineering, the Center for Advanced Regenerative Engineering, the Cancer and Physical Sciences Program at the Robert H. Lurie Comprehensive Cancer Center, and NIH Grants.