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Organic Chemistry Complete Course

Chad's Prep via YouTube

Overview

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Master the fundamentals of organic chemistry through comprehensive video lessons covering everything from basic molecular structure to advanced synthesis strategies. Learn Lewis structures, hybridization, and molecular orbital theory before progressing through functional group identification, stereochemistry, and reaction mechanisms. Explore substitution and elimination reactions (SN1, SN2, E1, E2), alkene and alkyne chemistry, and free radical processes. Develop proficiency in spectroscopic analysis using IR, NMR, and mass spectrometry to determine molecular structures. Study aromatic chemistry including electrophilic aromatic substitution, conjugated systems, and pericyclic reactions. Examine carbonyl chemistry through nucleophilic addition and acyl substitution reactions of aldehydes, ketones, carboxylic acids, and their derivatives. Investigate enolate chemistry including aldol reactions, Claisen condensations, and Michael additions. Cover amine chemistry, carbohydrate structures, and advanced synthetic methodology. Build retrosynthetic analysis skills to design multi-step organic syntheses. Understand chemical reactivity principles rather than memorizing isolated reactions, making organic chemistry concepts logical and interconnected.

Syllabus

1.1 Lewis Structures | Organic Chemistry Complete Course
1.2 Formal Charges | Organic Chemistry
1.3 Valence Bond Theory and Hybridization | Organic Chemistry
1.4 Molecular Orbital Theory (MO Theory) | Organic Chemistry
1.5 Polarity | Organic Chemistry
1.6 Intermolecular Forces | Organic Chemistry
2.1 Condensed Structures | Organic Chemistry
2.2 Drawing Line Angle Structures (aka Bond Line Structures) | Organic Chemistry
2.3 Identifying Functional Groups | Organic Chemistry
2.4 Resonance | Organic Chemistry
3.1 Introduction to Acids and Bases | Organic Chemistry
3.2 Ranking Acids and Bases | Organic Chemistry
4.1 IUPAC Nomenclature of Alkanes and Cycloalkanes | Organic Chemistry
4.2 Naming Complex Substituents | Organic Chemistry
4.3 IUPAC Nomenclature of Bicyclic Compounds | Organic Chemistry
4.4 Drawing Structural Isomers | Organic Chemistry
4.5 Newman Projections | Organic Chemistry
4.6 Cycloalkanes and Cyclohexane Chair Conformations | Organic Chemistry
5.1 Overview of Isomers | Constitutional Isomers and Stereoisomers | Organic Chemistry
5.2 How to Assign R and S Configuration | Absolute Configuration | Organic Chemistry
5.3 Molecules with Multiple Chiral Centers | Enantiomers, Diastereomers, and Meso Compounds | OChem
5.4 Fischer Projections | Organic Chemistry
5.5 How to Identify Type of Isomerism | Organic Chemistry
5.6 Amine Inversion and Chiral Molecules without Chiral Centers (Allene & Biphenyl) | Organic
5.7 Optical Activity | Organic Chemistry
6.1 Reaction Enthalpy and Bond Dissociation Energy | Organic Chemistry
6.2 Entropy, Gibbs Free Energy, and the Equilibrium Constant | Organic Chemistry
6.3 The Kinetics of Organic Reactions | Organic Chemistry
6.4 Nucleophiles, Electrophiles, and Intermediates | Organic Chemistry
6.5 Curved Arrow Pushing in Reaction Mechanisms | Organic Chemistry
7.1 SN2 Reaction | Organic Chemistry
7.2 SN1 Reactions | Organic Chemistry
7.3 SN1 vs SN2 | Organic Chemistry
7.4 Introduction to Elimination Reactions [Zaitsev's Rule and the Stability of Alkenes] | OChemistry
7.5 E2 Reactions | Organic Chemistry
7.6 E1 Reactions and E1 vs E2 | Organic Chemistry
7.7 How to Distinguish Between Substitution and Elimination Reactions (SN2 SN1 E2 E1) | OChem
8.0 Naming Alkenes IUPAC | Organic Chemistry
8.1 Introduction to Alkene Addition Reactions; Markovnikov's Rule and Syn vs Anti | OChemistry
8.2 Hydrohalogenation of Alkenes | Organic Chemistry
8.3 Acid Catalyzed Hydration, Oxymercuration Demercuration, and Hydroboration Oxidation | OChemistry
8.4 Addition of an Alcohol | Acid-Catalyzed Addition and Alkoxymercuration-Demercuration | OChem
8.5 Catalytic Hydrogenation of Alkenes and Heats of Hydrogenation | Organic Chemistry
8.6 Halogenation of Alkenes and Halohydrin Formation | Organic Chemistry
8.7 Expoxidation, Anti-Dihydroxylation, and Syn-Dihydroxylation of Alkenes | Organic Chemistry
8.8 How to Predict the Products of Alkene Addition Reactions | Organic Chemistry
8.9 Ozonolysis of Alkenes, Oxidation of Alkenes with KMnO4 | Oxidative Cleavage | Organic Chemistry
9.1 Naming Alkynes | Organic Chemistry
9.2 Acidity of Alkynes | Organic Chemistry
9.3 Synthesis of Alkynes | Organic Chemistry
9.4 Reduction of Alkynes | Organic Chemistry
9.5 Hydrohalogenation of Alkynes | Organic Chemistry
9.6 Halogenation of Alkynes | Organic Chemistry
9.7 Hydration of Alkynes | Organic Chemistry
9.8 Ozonolysis of Alkynes | Organic Chemistry
9.9 Alkylation of Acetylide Ions from Terminal Alkynes | Organic Chemistry
10.1 Free Radical Halogenation | Organic Chemistry
10.2 The Free Radical Halogenation Mechanism | Organic Chemistry
10.3 Allylic Bromination and Benzylic Bromination with NBS | Organic Chemistry
10.4 Addition of HBr and Peroxide | Organic Chemistry
11.1 Introduction to Organic Synthesis | Retrosynthesis | Organic Chemistry
11.2 Common Patterns in Organic Synthesis Involving Alkenes | Retrosynthesis | Organic Chemistry
11.3 Common Patterns in Organic Synthesis Involving Alkynes | Organic Chemistry
12.1 Naming Alcohols | Organic Chemistry
12.2 Properties of Alcohols | Organic Chemistry
12.3 Synthesis of Alcohols | Organic Chemistry
12.4 Grignard Reagents | Organic Chemistry
12.5 Protecting Groups for Alcohols | Organic Chemistry
12.6 Substitution Reactions of Alcohols | Organic Chemistry
12.7 Elimination Reactions of Alcohols | Organic Chemistry
12.8 Oxidation of Alcohols by Chromic Acid and PCC | Organic Chemistry
12.9 Organic Synthesis with Alcohols | Organic Chemistry
13.1 Naming Ethers | Organic Chemistry
13.2 Synthesis of Ethers | Organic Chemistry
13.3 Reactions of Ethers | Organic Chemistry
13.4 Naming Epoxides | Organic Chemistry
13.5 Synthesis of Epoxides | Organic Chemistry
13.6 Ring Opening of Epoxides | Organic Chemistry
13.7 Thiols | Organic Chemistry
13.8 Sulfides | Organic Chemistry
13.9 Organic Synthesis with Ethers and Epoxides | Retrosynthesis | Organic Chemistry
14.1 Introduction to IR Spectroscopy | Organic Chemistry
14.2a IR Spectra of Carbonyl Compounds | Organic Chemistry
14.2b The Effect of Conjugation on the Carbonyl Stretching Frequency | Organic Chemistry
14.3 Interpreting More IR Spectra | Organic Chemistry
14.4 Introduction to Mass Spectrometry | Organic Chemistry
14.5 Isotope Effects in Mass Spectrometry | Organic Chemistry
14.6a Fragmentation Patterns of Alkanes, Alkenes, and Aromatic Compounds | Mass Spectrometry
14.6b Fragmentation Patterns of Alkyl Halides, Alcohols, and Amines | Mass Spectrometry
14.6c Fragmentation Patterns of Ketones and Aldehydes | Mass Spectrometry
15.1 Introduction to NMR | Organic Chemistry
15.2 The Number of Signals in C 13 NMR | Organic Chemistry
15.3 The Number of Signals in Proton NMR | Organic Chemistry
15.4 Homotopic vs Enantiotopic vs Diastereotopic | Organic Chemistry
15.5a The Chemical Shift in C 13 and Proton NMR | Organic Chemistry
15.5b The Integration or Area Under a Signal in Proton NMR | Organic Chemistry
15.5c The Splitting or Multiplicity in Proton NMR | Organic Chemistry
15.6a Interpreting NMR Example 1 | Organic Chemistry
15.6b Interpreting NMR Example 2 | Organic Chemistry
15.6c Interpreting NMR Example 3 | Organic Chemistry
15.6d Structural Determination From All Spectra Example 4 | Organic Chemistry
15.6e Structural Determination From All Spectra Example 5 | Organic Chemistry
15.7 Complex Splitting | NMR | Organic Chemistry
16.1 Conjugated Systems and Heats of Hydrogenation | Organic Chemistry
16.2a Pi Molecular Orbitals of 1,3 Butadiene | Organic Chemistry
16.2b Pi Molecular Orbitals of the Allyl System | Organic Chemistry
16.2c Pi Molecular Orbitals of 1,3,5-Hexatriene | Organic Chemistry
16.3 UV/Vis Spectroscopy | Organic Chemistry
16.4 Electrophilic Addition to Conjugated Dienes | Organic Chemistry
16.5 Diels-Alder Reactions | Organic Chemistry
16.6 Cycloaddition Reactions | Organic Chemistry
16.7 Electrocyclic Reactions | Organic Chemistry
16.8 Sigmatropic Rearrangements | Organic Chemistry
17.1 Naming Benzenes | Organic Chemistry
17.2 Aromatic vs Antiaromatic vs Nonaromatic | Organic Chemistry
17.3 The Effects of Aromaticity on Reactivity | Organic Chemistry
17.4 Pi Molecular Orbitals of Benzene | Organic Chemistry
18.1 Electrophilic Aromatic Substitution (EAS Reactions) | Organic Chemistry
18.2 Friedel Crafts Alkylation and Acylation | Organic Chemistry
18.3 Ortho-Para Directors vs Meta Directors in EAS Reactions | Organic Chemistry
18.4 Catalytic Hydrogenation and the Birch Reduction | Organic Chemistry
18.5 Side Chain Reactions of Benzenes | Organic Chemistry
18.6 Nucleophilic Aromatic Substitution (NAS) | Organic Chemistry
18.7 Retrosynthesis with Aromatic Compounds | Organic Chemistry
19.1 Naming Ketones and Aldehydes | Organic Chemistry
19.2 Synthesis of Ketones and Aldehydes | Organic Chemistry
19.3 Introduction to Nucleophilic Addition of Ketones and Aldehydes | Organic Chemistry
19.4a Formation of Hemiacetals and Acetals (Nucleophilic Addition of Alcohols) | Organic Chemistry
19.4b Cyclic Acetals as Protecting Groups for Alcohols | Organic Chemistry
19.5 Imine and Enamine Formation | Addition of Amines | Organic Chemistry
19.6 Reduction of Ketones and Aldehydes (NaBH4 and LiAlH4) | Organic Chemistry
19.7a Addition of Grignard Reagents (and other Carbon Nucleophiles)
19.7b Wittig Reaction | Organic Chemistry
19.8 Baeyer Villiger Oxidation | Organic Chemistry
19.9 Retrosynthesis with Aldehydes and Ketones | Organic Chemistry
20.1 Naming Carboxylic Acids and Carboxylic Acid Derivatives | Organic Chemistry
20.2 Nucleophilic Acyl Substitution | Organic Chemistry
20.3 The Mechanisms of Nucleophilic Acyl Substitution | Organic Chemistry
20.4 Reaction with Grignard Reagents and Gilman Reagents | Carboxylic Acid Derivatives
20.5 Hydride Reduction Reactions | Carboxylic Acid Derivatives | Organic Chemistry
20.6 Synthesis and Reactions of Acid Halides | Organic Chemistry
20.7 Synthesis and Reactions of Acid Anhydrides | Organic Chemistry
20.8 Synthesis and Reactions of Esters | Organic Chemistry
20.9 Properties, Synthesis, and Reactions of Carboxylic Acids | Organic Chemistry
20.10 Synthesis and Reactions of Amides | Organic Chemistry
20.11 Synthesis and Reactions of Nitriles | Organic Chemistry
20.12 Retrosynthesis with Carboxylic Acids Derivatives | Organic Chemistry
21.1 Acidity of the Alpha Hydrogen | Organic Chemistry
21.2 Mechanisms of Alpha Substitution Reactions | Organic Chemistry
21.3 Alpha Halogenation | Organic Chemistry
21.4 Alpha Alkylation | Organic Chemistry
21.5 Aldol Reactions | Organic Chemistry
21.6 Claisen Condensation Reactions | Organic Chemistry
21.7 Malonic Ester Synthesis and Acetoacetic Ester Synthesis | Organic Chemistry
21.8 Michael Reactions | Organic Chemistry
21.9 Robinson Annulation | Organic Chemistry
21.10 Retrosynthesis with Enolates and Enols | Organic Chemistry
22.1 Naming Amines | Organic Chemistry
22.2 Basicity of Amines | Organic Chemistry
22.3 Synthesis of Amines | Organic Chemistry
22.4 Hofmann Elimination and Cope Elimination | Organic Chemistry
22.5 Sandmeyer Reactions | Organic Chemistry
22.6 EAS Reactions with Nitrogen Heterocycles | Organic Chemistry
22.7 Retrosynthesis with Amines | Organic Chemistry
24.1 Classification of Monosaccharides | Organic Chemistry
24.2 Reactions of Monosaccharides | Organic Chemistry
24.3 Disaccharides and Polysaccharides | Organic Chemistry

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