Explore how Novartis architected their regulated NextGen clinical trial data platform using AWS services in this 56-minute conference talk from AWS re:Invent 2025. Dive deep into their AWS-based clinical landscape implementation utilizing Amazon S3, Databricks on AWS, Amazon SageMaker, and AWS RDS to create a comprehensive data infrastructure. Discover their approach to data lake patterns and legacy system modernization while maintaining strict regulatory compliance requirements. Learn how they constructed a secure, traceable data backbone that powers AI and GenAI innovations across protocol design, trial performance management, and clinical document generation. Examine the architecture that enables clean data flow and rapid decision-making throughout drug development workflows, providing insights into how pharmaceutical companies can leverage cloud technologies to accelerate clinical research and drug discovery processes.