Explore how Novartis architected their regulated NextGen clinical trial data platform using AWS services including Amazon S3, Databricks on AWS, Amazon SageMaker, and AWS RDS in this 56-minute conference talk from AWS re:Invent 2025. Discover their comprehensive AWS-based clinical landscape and learn about their implementation of data lake patterns and legacy system modernization approach. Examine how they built a secure, traceable data backbone that powers AI and GenAI innovations in protocol design, trial performance management, and clinical document generation while maintaining strict regulatory compliance. Understand the architecture that enables clean data flow and rapid decision-making across drug development workflows, providing insights into modernizing clinical trial infrastructure for pharmaceutical companies looking to leverage cloud technologies and artificial intelligence in their drug development processes.