Porphyria Cutanea Tarda - Cause, Symptoms, Diagnosis and Treatment

Learn about porphyria cutanea tarda in this 14-minute educational video that comprehensively covers this specific type of porphyria caused by defects in heme synthesis pathways. Discover the underlying mechanisms, including the deficiency of uroporphyrinogen decarboxylase, and how it manifests with distinctive symptoms like photodermatitis (skin sensitivity to sunlight), vesicles, bullae, and characteristically dark purple urine. Understand the autosomal dominant inheritance pattern, association with hepatitis C, and the role of triggers such as iron overload and estrogens. Explore diagnostic approaches and treatment options including phlebotomy, chloroquine, and sun avoidance. The video is part of Medicosis Perfectionalis' comprehensive medical education series covering various aspects of pathophysiology and clinical medicine.