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Learn about the critical role of somatic mutations in human health through this 46-minute medical and population genetics primer lecture delivered by Ben Finander from Harvard Medical School, Boston Children's Hospital, and the Broad Institute. Explore how genetic changes that occur in somatic cells throughout an individual's lifetime impact disease development, progression, and treatment outcomes. Discover the mechanisms behind somatic mutation accumulation, their contribution to cancer and other diseases, and the latest research methodologies used to detect and analyze these mutations. Gain insights into how understanding somatic mutations is revolutionizing personalized medicine approaches and therapeutic strategies in clinical practice.
Syllabus
MPG: Somatic Mutations and Human Health (2025)
Taught by
Broad Institute