Broad Institute Courses

Leveraging Large Biobanks to Study Genetics of Human Traits and Diseases (2025)

1 rating

Discover how to leverage large biobanks for genetic studies of human traits and diseases with Wei Zhou from Broad Institute, MGH, and Harvard Medical School in this informative primer session.

• YouTube
• 48 minutes
• Self-Paced
• Free Video

Individual-level Tissue-Specific Imputed Transcriptomes in Drug Target Prioritization and Disease Risk Prediction

1 rating

Explore tissue-specific transcriptomes for drug target prioritization and disease risk prediction. Learn about TWAS, co-localization, polygenic risk scores, and phenome-wide scans in genetics research.

• YouTube
• 39 minutes
• Self-Paced
• Free Video

Taking an Engineer's Approach to Understanding Biology

1 rating

Explore how engineering approaches yield new perspectives on biological systems, enabling innovative measurements and insights into cellular and tissue function.

• YouTube
• 1 hour 20 minutes
• Self-Paced
• Free Video

A Practical Primer on Bayesian Statistics (2025)

Discover the fundamentals of Bayesian statistics in biomedical research with Sarah Urbut from MGH and Broad Institute, covering biobank development principles and applications in medical and population genetics.

• YouTube
• 46 minutes
• Self-Paced
• Free Video

Molecular Glues - From Protein Degradation to Transcription Factor Reprogramming

Explore molecular glues in chemical biology, focusing on new transcription factor targeting compounds that reprogram Bcl-6 from a repressor to an activator, inducing apoptosis in lymphoma models at picomolar concentrations.

• YouTube
• 1 hour 3 minutes
• Self-Paced
• Free Video

CocycleHunter: A Topological and Geometric Tool for Phase Estimation in Single-Cell RNA-seq Data

Discover how CocycleHunter uses topological and geometric approaches for phase estimation in single-cell RNA-seq data in this colloquium by Kathryn Hess Bellwald, exploring the intersection of machine learning and biomedical research.

• YouTube
• 1 hour 4 minutes
• Self-Paced
• Free Video

Structured Variational Autoencoders for Prediction and Optimization; Diffusion for Molecule Generation - Primer

Explore structured variational autoencoders for prediction and optimization, along with diffusion models for molecule generation in drug discovery, focusing on deep generative models and their applications in temporal data modeling.

• YouTube
• 1 hour 44 minutes
• Self-Paced
• Free Video

Searching through Materials: Generate, Emulate, Simulate

Explore Max Welling's insights on materials research through generation, emulation, and simulation techniques in this MIT-Harvard colloquium on machine learning applications in biomedical research.

• YouTube
• 1 hour 2 minutes
• Self-Paced
• Free Video

Automating Chemistry With LLM-Based Agents

Explore how LLM-based scientific agents automate chemistry tasks, from molecular design to protein simulations, surpassing human performance in literature research and bioinformatics analysis.

• YouTube
• 1 hour 23 minutes
• Self-Paced
• Free Video

Machine Learning for Reconstructing Structural Landscapes from CryoEM

Explore machine learning techniques for cryo-EM structural reconstruction and heterogeneous biomolecular complex visualization with cryoDRGN system insights.

• YouTube
• 1 hour 42 minutes
• Self-Paced
• Free Video

Spatial Transcriptomics Technologies - A Primer

Discover spatial transcriptomics technologies and their applications in medical genetics through expert insights from the Broad Institute's genetics primer series.

• YouTube
• 51 minutes
• Self-Paced
• Free Video

How Brain Cells Talk to One Another

Explore how brain cells communicate and the implications for disorders like schizophrenia and Alzheimer's. Nehme discusses lab methods for studying neural cross-talk while Wang examines sugar-based messaging systems in neurodegenerative disorders.

• YouTube
• 55 minutes
• Self-Paced
• Free Video

Exploring Life's Structures Across Scales Through Imaging

Discover how Jennifer Lippincott-Schwartz explores biological structures across different scales through advanced imaging techniques in this insightful talk from the Eric and Wendy Schmidt Center Symposium.

• YouTube
• 37 minutes
• Self-Paced
• Free Video

Deep Learning the Cis-Regulatory Code at Single Base and Single Cell Resolution

Discover deep learning approaches for decoding cis-regulatory genetic code at single base and cell resolution with Stanford's Anshul Kundaje.

• YouTube
• 36 minutes
• Self-Paced
• Free Video

Bridging Biology and AI for Genome Design

Discover how Patrick Hsu bridges biology and AI for genome design in this invited talk from the Eric and Wendy Schmidt Center Symposium on Biomedical Science and AI.

• YouTube
• 33 minutes
• Self-Paced
• Free Video