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Explore a classical-first approach to quantum chemistry in the early fault-tolerant quantum computing era through this 49-minute conference talk. Learn how to bridge NISQ-style workflows with early fault-tolerant quantum computation (FTQC) when quantum resources are limited and every qubit and gate counts. Discover how state-of-the-art classical solvers provide uncertainty-quantified baselines for target selection and compact wavefunction representations that reduce quantum state-preparation costs. Examine compact determinant expansions and benchmark studies that create reproducible classical references for challenging catalytic and transition-metal systems. Understand hybrid approaches including loading compact expansions on fault-tolerant devices and refining them through quantum projection methods such as imaginary-time evolution and phase-estimation variants. Investigate non-orthogonal eigensolvers that combine multiple classical states with quantum-generated states to create transparent workflows for selecting early-FTQC targets and making testable competitiveness claims in quantum chemistry applications.
