Checkpoint Molecules, Tregs and Induction of Anti-tumor Immunity

Join a 59-minute webinar led by Dr. Vijay Kuchroo, the Samuel L. Wasserstrom Professor of Neurology at Harvard Medical School, exploring the complex relationship between checkpoint molecules, regulatory T cells (Tregs), and anti-tumor immunity. Discover how co-inhibitory receptors like CTLA-4 and PD-1 maintain immune homeostasis, and learn about newly identified checkpoint molecules including Tim-3, Lag-3, and TIGIT. Explore cutting-edge research revealing how these checkpoint molecules function as a coordinated module in CD8+ T cells and FoxP3+ Tregs, impacting both autoimmunity and cancer treatment outcomes. Gain insights into the latest findings on conditional deletion of checkpoint molecules in various cell types and their implications for tumor growth and anti-tumor immunity. Master the regulation of checkpoint molecule expression in the immune system, understand their impact on CD8+ T cell function, and examine their role in FoxP3+ regulatory T cells.