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Explore how aging affects immune function and cancer control in this 22-minute webinar presented by Dr. Debattama Sen from Massachusetts General Hospital Center for Cancer Research and Harvard Medical School. Discover the mechanisms behind age-related decline in immune function that coincides with increased cancer rates in older populations. Learn about groundbreaking research revealing how tumor growth accelerates in older tumor-bearing mice due to diminished infiltration and function of CD8+ T cells. Understand the precise reasons behind age-related dysfunction of CD8+ T cells in cancer contexts and examine the complex interactions within the aged tumor microenvironment that limit effective immune responses. Gain insights into how the aging process compromises the body's natural ability to control cancer through T cell-mediated immunity, with implications for developing age-specific cancer treatment strategies and immunotherapies.
