A Bridge Too Far: How Dps Protein From E. coli Condenses DNA

A Bridge Too Far: How Dps Protein From E. coli Condenses DNA

BPPB Seminar via YouTube Direct link

Ising model can explain hysteresis

7 of 11

7 of 11

Ising model can explain hysteresis

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A Bridge Too Far: How Dps Protein From E. coli Condenses DNA

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  1. 1 Intro
  2. 2 Life is hard for single celled organisms.
  3. 3 Stressed bacteria produce Dps, a DNA binding protein
  4. 4 Dps is a dodecamer (12mer) with a ferroxidase enzymatic function
  5. 5 Dps protects bacteria in times of stress
  6. 6 Single molecule condensation assay
  7. 7 Ising model can explain hysteresis
  8. 8 We can identify different topologies in the
  9. 9 Dps binds with different rates to different toplog
  10. 10 Ising-like cooperativity gives single condensed structure
  11. 11 Why does Dps prefer supercoiled DNA

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