Coursera Flash Sale
40% Off Coursera Plus for 3 Months!
Grab it
Explore the cutting-edge application of Organ-on-a-Chip technology for modeling CAR T-cell therapy in solid tumors through this 36-minute keynote webinar. Learn how researchers are addressing the critical challenges of CAR T-cell therapy adaptation for solid tumors, including antigen heterogeneity, immunosuppressive microenvironments, and T-cell exhaustion. Discover how Emulate's validated Organ-Chip workflow enables comprehensive modeling of the entire CAR T-cell therapy journey, from vascular administration to tumor site migration - a crucial process that cannot be replicated in conventional cell cultures. Gain insights into the newly launched CAR T Organ-Chip workflow that allows researchers to study CAR T-cell therapy administration, vascular attachment, migration, and antigen-specific killing within a single vascularized cancer cell line model. Follow along as Dr. Anita Mehta, Principal Scientist at Emulate with over 13 years of oncology and immuno-oncology research experience, presents data-driven demonstrations of this innovative technology's capabilities. Understand how this breakthrough approach addresses the often-overlooked yet rate-limiting step of CAR T-cell extravasation from the bloodstream to tumor sites, providing researchers with more effective tools for developing solid tumor treatments.
