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Attend this keynote webinar presentation exploring advanced CAR T cell engineering strategies for enhanced cancer treatment effectiveness. Learn from Dr. Sarwish Rafiq, Assistant Professor at Emory School of Medicine's Department of Hematology and Medical Oncology, as she presents cutting-edge research on developing metabolically optimized CAR T cells with improved memory characteristics. Discover how novel engineering methods can create CAR T cells enriched with memory phenotypes that demonstrate superior metabolic fitness for treating both hematological malignancies and solid tumors. Explore the challenges facing current CAR T cell therapies, including the complex immunosuppressive tumor microenvironments and checkpoint pathway exploitation that allow tumors to evade immune responses. Understand why only a subset of patients achieve durable complete responses with existing CAR T cell treatments and how these innovative approaches aim to overcome significant obstacles in solid tumor treatment. Participate in the live Q&A session to engage directly with the research findings and gain insights into the translational applications of these mechanistic discoveries in immune effector cell function against cancer cells within tumor microenvironments.
Syllabus
Keynote Presentation: Engineering Metabolically Fit, Memory-Rich CAR T cells for Treatment of Cancer
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