Derisk Early and Accelerate Antibody Development with Mass Photometry - Column-Free Aggregation Assessment and In Solution Binding Mechanisms

Learn to accelerate antibody development using mass photometry for column-free aggregation assessment and binding mechanism analysis in this 45-minute webinar presented by Dr. Michael Fiebig, Chief Scientific Officer at Absolute Antibody. Discover how mass photometry (MP) compares to SEC-HPLC in determining antibody purity and aggregation across different antibody formats, with MP providing superior resolution on oligomeric states as a single particle measurement technique. Explore cases where MP delivers fast, reliable assessment of antibody purity and aggregation when SEC-HPLC cannot provide meaningful data. Examine antibody-antigen binding mechanisms of monoclonal antibodies (mAbs) and bispecific antibodies (bsAbs), and understand how mass photometry can measure binding stoichiometry and binding affinities associated with different stoichiometries. Gain insights from Dr. Fiebig's extensive experience in recombinant antibody development, protein engineering methods, and advanced sequencing techniques developed during his tenure at Absolute Antibody since 2014.