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Explore advanced mass spectrometry methodologies for biologics drug discovery and optimization in this 45-minute webinar. Learn how mass spectrometry addresses the complexity and heterogeneity of protein therapeutics, where post-translational modifications and sequence variants can significantly impact product quality, safety, and efficacy. Discover high-throughput intact mass analysis, peptide mapping, and glycan analysis techniques for both qualitative physicochemical characterization and quantitative analysis in target validation and pharmacokinetic assessment. Examine real-world case studies demonstrating how these approaches provide comprehensive structure and function insights to drive more definitive biologics discovery and optimization. Understand how mass spectrometry delivers in-depth protein characterization to guide discovery, engineering, and optimization processes, supports robust in vitro and in vivo pharmacokinetic analysis to mitigate development risks, and addresses early-stage developability challenges through tailored analytical workflows.
