Avectas' Solupore Transfected Cells Isolated Using Sony's CGX10 Yield Highly Cytotoxic CAR-T Cells

Learn how CAR-T cells transfected using Solupore® technology from Avectas and sorted using Sony's CGX10 Cell Isolation System outperform unsorted cells in single-cell, image-based targeted killing assays. Discover how this integrated workflow enriches triple-positive CD45RA+, CD62L+, CCR7+ T stem cell memory cells (TSCM) with high purity and viability, consistently demonstrating superior functionality compared to unsorted cells. Explore how the CGX10 system integrates both upstream and downstream from the Solupore-based workflow, supporting a streamlined and scalable process for generating potent CAR-T cell therapies. Examine the CGX10's fully closed cell isolation system designed for GMP-compliant cell production and sorting applications, featuring seamless scalability from process development to clinical-scale manufacturing. Understand how Avectas' Solupore technology enhances patient access to autologous T-cell therapies by delivering payloads via a physicochemical mechanism that reversibly permeabilizes the cell membrane, producing healthier engineered cells with a younger memory phenotype. Review comprehensive data showing the yield of highly cytotoxic CAR-T products and see how the Solupore process generates healthier, more potent transfected T cells. This 51-minute session is ideal for scientists and clinicians working in cell therapy including CAR-T, Treg, NK, and stem cell applications, particularly those interested in non-viral technology for cell engineering and multiparametric selection workflows in research, process development, or manufacturing stages.