Condensates of Charged Macromolecules - Assembly, Dynamics, and Transport

Attend this colloquium lecture exploring the fascinating world of biomolecular condensates formed by intrinsically disordered proteins (IDPs). Discover how these charged macromolecules spontaneously assemble into membrane-less organelles through liquid-liquid phase separation. Learn about the fundamental principles governing charge regulation, structural organization, and hierarchical dynamics within these condensates. Examine single-molecule electrophoretic mobility and transport phenomena that characterize these biological systems. Gain insights from theoretical frameworks and their comparison with experimental observations in this cutting-edge field of polymer science and biophysics. The presentation is delivered by Prof. M. Muthukumar, a distinguished expert in polymer science from the University of Massachusetts, Amherst, who brings decades of research experience and numerous accolades including the Dillon Medal and Polymer Physics Prize from the American Physical Society.