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Explore the dynamics of biomolecular complex coacervates across multiple scales in this 41-minute conference talk by Ben Schuler from the University of Zurich. Delve into how living cells coordinate molecular activity through membrane-less compartments called biomolecular condensates, which play crucial roles in gene expression, signal transduction, and neurotransmission. Examine the current understanding of molecular interactions leading to condensation and investigate how the emergent physical properties of these condensates mediate their biological functions. Learn about theoretical frameworks and simulation approaches for describing biomolecular condensates, discover new experimental methods for characterizing these structures, and understand the physicochemical principles that shape their formation. Address the challenges in mapping computational and laboratory-based droplet studies to actual condensates within living cells, while exploring the diverse lifetimes, sizes, mechanochemical properties, and architectures exhibited by these biological compartments.
