Coursera Flash Sale
40% Off Coursera Plus for 3 Months!
Grab it
Explore the fundamental principles governing active processes within biomolecular condensates and droplets in this 31-minute conference talk. Delve into how living cells utilize membrane-less compartments to coordinate molecular activities across space and time, examining the diverse biological functions these condensates serve including gene expression, signal transduction, and neurotransmission. Investigate the wide range of properties exhibited by condensates, from their varying lifetimes and sizes to their mechanochemical characteristics and architectural features. Learn about the current challenges in understanding how the emergent physical properties of condensates mediate their biological functions, despite advances in characterizing molecular interactions that lead to condensation. Discover theoretical frameworks and simulation approaches being developed to describe biomolecular condensates, while examining new experimental methods for characterizing these structures and delineating their functions. Gain insights into physicochemical principles that shape condensate behavior and address the ongoing challenges in mapping computational and in vitro droplet studies to actual condensates within living cells.
