The Physics and Biophysics of Molecular Motor Dynein and Role of Thermal Fluctuations
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Watch a detailed scientific lecture from Stanford University's Steven Chu exploring the intricate mechanisms of molecular cargo transport in neuronal cells, with particular focus on the dynein motor protein. Learn about groundbreaking experimental techniques using bright optical probes that achieve unprecedented 4nm spatial and 1ms temporal resolution in tracking molecular movements in live neurons. Discover a novel chemo-mechanical model involving sequential ATP hydrolysis and understand how thermal fluctuations are harnessed for cargo transport. Examine ongoing research aimed at pushing resolution boundaries to 0.3nm spatially and 2 microseconds temporally to validate theoretical predictions about molecular motor function.
Syllabus
The physics and biophysics of molecular motor dynein and role of thermal fluctuations
Taught by
Centre for Quantum Technologies