Logistic-Moran Modeling of Evolutionary Dynamics and Therapy Response

Explore a mathematical modeling approach that combines logistic growth and Moran processes to analyze evolutionary dynamics in clonal hematopoiesis and predict therapy responses in this 16-minute conference talk. Discover how quantitative fitness models can be applied to understand the complex evolutionary processes occurring in blood cell development and how these insights inform therapeutic strategies. Learn about the mathematical frameworks used to model population dynamics in hematopoietic systems, examine the interplay between clonal evolution and treatment outcomes, and understand how logistic-Moran models provide valuable predictions for clinical applications in hematological disorders.