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Learn about the experimental framework and data structure for the Obesity Machine Learning Challenge in this 11-minute lecture from the Broad Institute. Explore how CRISPR/Cas9 gene perturbation experiments are designed to study adipocyte cell fate decisions, understanding the specific methodologies used to generate the dataset you'll work with in this competition focused on tackling metabolic diseases. Gain insights into the experimental protocols that produce data on how genetic modifications influence whether adipocytes become energy-storing or energy-burning cells, providing essential context for developing machine learning models to predict gene perturbation effects on these obesity-related cellular processes.
Syllabus
Obesity ML Competition: Lecture 3, Part A - Data - Experiment Overview
Taught by
Broad Institute