Obesity ML Competition - Gene Expression Programs Technology - Lecture 2, Part A

Learn about gene expression programs in this 12-minute technical lecture from the Broad Institute's Obesity Machine Learning Challenge series. Explore the molecular mechanisms underlying gene expression and how they relate to adipocyte biology and metabolic diseases. Gain essential technical knowledge about gene perturbation effects using CRISPR/Cas9 technology and understand how gene expression programs influence the differentiation of adipocytes into energy-storing or energy-burning cells. Discover the computational approaches used to analyze gene expression data in the context of obesity research, preparing you with the biological and technical foundation needed to predict how genetic modifications affect cellular fate in adipocytes for the machine learning competition focused on tackling metabolic diseases.