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Yale University

Epoxide Opening, Dipolar Cycloaddition, and Ozonolysis in Organic Chemistry

Yale University via YouTube

Overview

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This course analyzes mechanisms of epoxide ring opening, alkene ozonolysis, 1,3-dipolar cycloaddition, acetal hydrolysis, carbonyl attack, and alkene dihydroxylation. It emphasizes orbital symmetry, regiospecificity, and interpretation of experimental data.

Syllabus

- Chapter 1. Regiospecificity in Epoxide Opening: Interpreting Experimental Data
.
- Chapter 2. Ozonolysis and 1,3-Dipolar Cycloaddition
.
- Chapter 3. Acetal Hydrolysis and the Completion of Ozonolysis
.
- Chapter 4. Electrophilic Participation in Nucleophilic Attack on C=O
.
- Chapter 5. Cycloaddition for Dihydroxylation
.

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