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Explore genetic reprogramming and induced pluripotent stem (iPS) cells in this 30-minute lecture that examines the fundamental mechanisms of cellular reprogramming and its applications in regenerative medicine. Learn about the process of converting differentiated cells back to a pluripotent state and understand how induced pluripotency factors (iPFs) function during tissue development. Discover the critical roles of Hox genes in determining cell fate and body plan organization, and investigate how disruptions in these regulatory networks can lead to homeotic transformations where one body part develops characteristics of another. Examine stem cell niches and their microenvironments that maintain stem cell populations, and explore how understanding these concepts contributes to advances in stem cell biology and tissue engineering applications for therapeutic purposes.
