Overview
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Explore the critical functions of Delta-Notch signaling pathways in tissue regeneration processes through this 30-minute educational video lecture. Examine how Delta-Notch communication between cells regulates stem cell maintenance, cell fate determination, and tissue patterning during regenerative responses. Discover the molecular mechanisms by which Notch receptors and Delta ligands coordinate cellular decisions that enable damaged tissues to restore their structure and function. Learn about the evolutionary conservation of these signaling networks across different regenerative systems and understand how disruptions in Delta-Notch signaling can impair regenerative capacity. Analyze experimental evidence from various model organisms that demonstrates the essential role of this pathway in controlling the balance between cell proliferation and differentiation during tissue repair and regeneration.
Syllabus
W7L34_Roles of Delta-Notch signaling during regeneration
Taught by
NPTEL-NOC IITM