Retina Regeneration - Importance of Shh Signaling and Epigenetic Factors

Learn about retina regeneration mechanisms through this 30-minute lecture focusing on the critical role of Sonic hedgehog (Shh) signaling pathways in retinal tissue repair and regeneration. Explore the importance of Shh signaling during retina regeneration processes and understand how morpholino-mediated gene knockdowns are used as research tools to study regenerative mechanisms. Examine the roles of epigenetic factors and their specific involvement in regeneration, with particular attention to let-7 miRNA and its regulatory functions in controlling Shh signaling pathways that are essential for successful retinal regeneration.