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Explore contact-mediated bidirectional receptor tyrosine kinase signaling in this 28-minute lecture from NPTEL-NOC IITM. Delve into the mechanisms of contact-mediated RTK signaling, focusing on Eph receptors and Ephrin ligands. Learn how these molecular interactions facilitate bi-directional signaling pathways that are crucial for cellular communication and development. Understand the unique properties of this signaling system where both the receptor and ligand can transmit signals, creating complex regulatory networks essential for processes such as axon guidance, cell migration, and tissue patterning.
