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Explore the molecular mechanisms underlying tissue regeneration through position control genes in this 30-minute lecture. Examine how anterio-posterior gradients establish spatial organization during regenerative processes and understand the critical role of position control genes in muscle development and maintenance. Investigate the cellular responses triggered when tissue is missing or damaged, focusing on the sophisticated signaling pathways that coordinate regeneration. Delve into ERK (Extracellular signal-Regulated Kinase) signaling cascades and their essential functions in controlling cell proliferation, differentiation, and tissue patterning during regenerative events. Analyze the integration of positional information with growth factor signaling to achieve precise tissue reconstruction and functional recovery.
Syllabus
W3L14_Position control genes and regeneration-Part B
Taught by
NPTEL-NOC IITM