Mapping the Regulatory Wiring of the Genome to Link Variants to Functions

Explore the regulatory architecture of the genome and its role in linking genetic variants to biological functions in this conference talk from the Variant to Function (V2F) Symposium. Learn how genetic associations can be translated into actionable therapeutic targets through advanced mapping techniques of genomic regulatory networks. Discover cutting-edge approaches to understanding how genetic variants influence gene expression and cellular function, with implications for developing biomarkers and patient stratification assays. Gain insights into the intersection of genomics, regulatory biology, and precision medicine as presented by Jesse Engreitz, Assistant Professor of Genetics at Stanford University and researcher at the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease. Understand the challenges and opportunities in moving from genome-wide association studies to functional understanding of disease mechanisms, and explore how regulatory genomics can accelerate genetically-informed approaches in healthcare and drug development.