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Explore the cutting-edge translation of high-resolution microelectrode technologies from research laboratories to clinical applications in human neuroscience research in this 32-minute webinar. Learn how advanced recording devices like Neuropixels have revolutionized spatial resolution capabilities, improving from 150 µm to 20-50 µm contact-to-contact spacing with enhanced customization options. Discover the decade-long journey of bringing these sophisticated devices into clinical settings and examine their potential to provide unprecedented insights into normal brain circuits, cognitive processes, and neurological pathologies. Examine the clinical implications and applications of these technologies, including their use in deep brain stimulation (DBS) and neuroprosthetics development. Understand how high-resolution intracranial recordings are being used to study neural and cognitive processing in the human brain, including investigations into how direct electrical stimulation affects neural processing and behavior. Consider the neuroethical considerations involved in translating experimental neurotechnology to human subjects and explore future directions for uncovering new answers about brain function and potentially discovering questions that weren't previously possible to investigate without these advanced devices. Gain insights from Dr. Angelique C. Paulk's multidisciplinary approach combining technological development with rigorous scientific methodology, drawing from her extensive research experience in neurophysiology, neuroscience, and behavior across multiple institutions and her current work with intracranial data at Massachusetts General Hospital.
Syllabus
Translating High-Resolution Devices to Understand Cognition and Neuropathologies in the Human Brain
Taught by
Labroots