How Do Epithelial Tissues Acquire and Change Their Shape

Explore the fundamental mechanisms behind epithelial tissue morphogenesis in this 29-minute seminar presentation from the Biological Physics/Physical Biology series. Delve into the complex processes that govern how epithelial tissues initially acquire their characteristic shapes and subsequently undergo morphological changes throughout development and physiological processes. Learn about the cellular and molecular mechanisms that drive tissue deformation, including cell division patterns, cell rearrangements, and mechanical forces that collectively sculpt epithelial architecture. Examine the interplay between physical constraints and biological signaling pathways that coordinate tissue-level shape changes, and discover how these processes are regulated during embryonic development, wound healing, and disease states. Gain insights into cutting-edge research methodologies used to study tissue mechanics and morphogenesis, including live imaging techniques and computational modeling approaches that help unravel the principles governing epithelial tissue organization and transformation.