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This lecture from the Santa Fe Institute explores the complex interplay between morphogenesis and morphogen patterning during embryonic development. Presented by Mattia Serra from the University of California, San Diego, discover how coordinated cell movements integrate with morphogen patterning and cell differentiation during embryogenesis. Learn about a new mathematical framework for understanding morphogen patterning in dynamic tissues that reformulates advection-reaction-diffusion models in cells' reference frames. Explore how this framework elucidates morphogen transport and compartmentalization, formalizes cell-cell signaling ranges in moving tissues, introduces new nondimensional numbers to assess morphogenetic effects on patterning, and clarifies the role of cell density dynamics in pattern formation. See applications to classic patterning models, morphogenetic motifs, and avian gastrulation data that provide quantitative perspectives for understanding dynamic tissue patterning in both natural and synthetic embryos.
