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Explore a comprehensive lecture on strengthening the nuclear nonproliferation regime presented by Frank von Hippel from Princeton University at the APS March Meeting 2019 in Boston, MA. Delve into the historical context of nuclear nonproliferation efforts, beginning with the 1946 Acheson-Lilienthal Report and its proposal for a nuclear-weapon-free world. Examine the three "dangerous" activities identified in the report: uranium mining, plutonium separation, and uranium enrichment. Learn about the challenges faced in implementing international control over these dual-use activities. Analyze the current global landscape of nuclear-related activities, including the status of plutonium separation and uranium enrichment in various countries. Consider the potential for phasing out national plutonium separation and enrichment plants as a means to strengthen the nonproliferation regime. Gain insights into the complexities of nuclear policy and the ongoing efforts to prevent the spread of nuclear weapons.