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Explore groundbreaking research on the vagus nerve and its crucial role in body-brain communication through this 55-minute Presidential Lecture by Stephen Liberles from the Simons Foundation. Discover how genetic approaches in mouse models have revealed the striking diversity of sensory neurons throughout the heart, lungs, and gastrointestinal tract, and learn about the novel body-brain reflexes that govern autonomic function. Examine the mechanisms underlying classical reflexes and understand how bodily signals are organized within the brain, including the identification of new sensory receptors and signaling pathways. Gain insights into the fundamental principles of neurophysiology that emerge from mapping these communication networks, and consider the potential therapeutic applications for treating autonomic diseases through a deeper understanding of how the brain monitors and responds to internal bodily states.
