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Explore how cryo-electron microscopy is revolutionizing cellular and structural biology in this comprehensive webinar presented by Marc Storms, a virology PhD with extensive experience in developing hardware and software solutions for electron microscopy platforms including the Vitrobot, Krios, Arctica, and Glacios systems. Discover how cryo-EM has transformed our understanding of molecular machinery by enabling three-dimensional structural analysis of biological molecules and complexes at atomic resolution. Learn about the technology's impact on rational vaccine and therapeutic design through high-throughput, high-resolution screening and data collection capabilities. Examine how cryo-EM allows researchers to observe protein structures and biomolecular complexes in-situ within cells and tissue, providing unprecedented insights into spatial connections and functional states within whole cellular contexts. Gain insights from an expert who has contributed to the development of key cryo-EM technologies including single particle analysis software (EPU), contrast enhancement methods like the Volta phase plate, cold-FEG systems, and multiple generations of Eagle cameras and Falcon direct electron detectors.