Cryo-Electron Microscopy Courses and Certifications

Simons Foundation

Mathematics of Cryo-Electron Microscopy

Explore mathematical principles and computational methods for cryo-EM reconstruction, focusing on small molecules and flexible structures in structural biology.

• YouTube
• 59 minutes
• On-Demand
• Free Video

Labroots

Simultaneous Polyclonal Antibody Sequencing and Epitope Mapping by Cryo-Electron Microscopy and Mass Spectrometry

Discover how to characterize antigen-specific antibody repertoires using cryo-electron microscopy and mass spectrometry, with insights into ModelAngelo's deep-learning capabilities for antibody sequencing and epitope mapping.

• YouTube
• 1 hour
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Machine Learning for Determining Protein Structure and Dynamics from Cryo-EM Images

Explore machine learning techniques for analyzing cryo-EM images to determine protein structure and dynamics, focusing on the cryoDRGN algorithm and its applications in structural biology.

• YouTube
• 49 minutes
• On-Demand
• Free Video

Broad Institute

Mechanism of a Protein Antibiotic in Bacteriophage Lysis - Broad-MIT Seminar 2023

Explore the mechanism of protein antibiotics through the study of bacteriophage lysis proteins, focusing on Protein E's inhibition of MraY and its implications for novel therapeutic development.

• YouTube
• 1 hour 4 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Spectral Decomposition of Atomic Structures in Heterogeneous Cryo-EM

Innovative approach to recover 3D atomic structures of flexible macromolecules from cryo-EM data, combining biological knowledge with spectral analysis to estimate conformational variations.

• YouTube
• 51 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Inference Poses for Reconstruction of 3D Molecular Volumes from Cryo-EM Images

Explore innovative techniques for reconstructing 3D molecular structures from cryo-EM data, focusing on the cryoAI algorithm that combines machine learning and physics-based approaches for efficient processing of large datasets.

• YouTube
• 46 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Molecular Structure Extrapolation to Zero Dose with CryoEM - IPAM at UCLA

Explore zero-dose extrapolation in cryoEM, enhancing structural detail and insights into radiation damage for improved molecular visualization and atomic model refinement.

• YouTube
• 43 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Approaches for Exploring the Geometry of Molecular Conformations in Cryo-EM

Explore advanced techniques for analyzing molecular conformations in cryo-electron microscopy, focusing on emerging approaches for complex conformational heterogeneity and associated challenges.

• YouTube
• 43 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Unbiasing Procedures for Scale-Invariant Multi-Reference Alignment - IPAM at UCLA

Explore unbiasing techniques for scale-invariant multi-reference alignment in signal processing, focusing on applications in cryo-electron microscopy and distribution learning from biased, sparse batches.

• YouTube
• 51 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Detection of Objects in Cryo-Electron Micrographs Using Geometric Deep Learning

Explore geometric deep learning techniques for object detection and segmentation in cryo-electron micrographs, focusing on unsupervised methods and graph-based transformers for complex structures.

• YouTube
• 43 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

High Throughput, High Performance Algorithms for High Resolution Subtomogram Averaging

Explore high-performance algorithms for subtomogram averaging in cryo-electron microscopy, focusing on tools like TomoBEAR and SUSAN to enhance throughput and resolution in structural biology.

• YouTube
• 47 minutes
• On-Demand
• Free Video

Labroots

Next Gen Cryo-EM - Advancing Cellular and Structural Biology

Discover how cryo-electron microscopy revolutionizes structural biology, enabling atomic-resolution 3D visualization of proteins and complexes within cells for drug design.

• YouTube
• 1 hour 14 minutes
• On-Demand
• Free Video

Imperial College London

Big Questions, Tiny Machines: Exploring Proteins and Cellular Functions

Delve into the fascinating world of proteins, exploring how these "tiny machines" drive cellular functions and how immune proteins attack bacteria while protecting human cells.

• YouTube
• 58 minutes
• On-Demand
• Free Video

IEEE Signal Processing Society

Cryo-Electron Microscopy and Single Particle Analysis - Webinar 3

Explore cryo-electron microscopy for high-resolution imaging of biosamples, including principles, challenges, and advanced reconstruction techniques like CryoGAN for structural analysis.

• YouTube
• 1 hour 19 minutes
• On-Demand
• Free Video

Institute for Pure & Applied Mathematics (IPAM)

Algorithms for Non-Local Filtering - Application Cryo-Electron and Biological Microscopy

Efficient algorithms for non-local filtering in microscopy, focusing on fast implementations of Non-Local Means Denoising and feature detection in biological images for improved image processing and analysis.

• YouTube
• 1 hour 20 minutes
• On-Demand
• Free Video