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Learn about the Developmental GTEx Project in this 43-minute educational talk from the Broad Institute's Medical and Population Genetics Primer series. Explore how this project extends the Genotype-Tissue Expression (GTEx) initiative to study gene expression patterns during human development across different tissues and developmental stages. Discover the methodologies used to analyze developmental gene expression data, understand the challenges of studying human developmental biology, and examine how this research contributes to our understanding of genetic variation's impact on development and disease susceptibility. Gain insights into the technical approaches for collecting and analyzing developmental tissue samples, the statistical methods employed to identify developmentally regulated genes, and the implications for understanding congenital disorders and developmental abnormalities. Examine how developmental GTEx data integrates with existing genomic resources and its applications in medical genetics research. This presentation is part of the Broad Institute's weekly primer series designed to provide in-depth introductions to complex trait genetics topics for research technicians, graduate students, postdoctoral fellows, and investigators entering the field of medical and population genetics.
