Leveraging Advancements in Genomics to Prevent Gastric Cancer

This talk examines how cellular genomics, including spatial transcriptomics, can map gene expression and cell types in gastric intestinal metaplasia. It compares these findings with dysplasia and cancer to identify genomic changes associated with cancer risk.

Syllabus

Intro
Long term objectives
Overview
Progression
Integrative cellular genomics
Conventional gene expression
Study samples
Histopathology comparison
Spatial transcriptomics - cell mapping
Localizing gene expression to cell type
Comparison with gastric cancer
Gene mapping
Mapping to metaplasia - high risk genes
Mapping to metaplasia - high cell resolution
Mapping to dysplasia and cancer
Gastric intestinal metaplasia analysis
Epithelial cell type assignment
Cell mapping of metaplasia components
Summary
Acknowledgements
Support