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Explore humanized immune system (HIS) mice models and their critical applications in preclinical research through this 49-minute keynote webinar. Learn about specialized host strains expressing human cytokines, particularly the hIL-2 NOG and hIL-15 NOG models that enhance T cell and natural killer (NK) cell engraftment for sophisticated immunological studies. Discover how these models support research in graft versus host disease and immuno-oncology applications. Examine the specific applications of hIL-2 NOG models for tumor-infiltrating lymphocyte (TIL) and CAR-T cell therapies, while understanding how hIL-15 NOG models advance NK cell research including NK cell therapies and NK cell-modulating drug development. Gain insights from Dr. Jessica Ramadhin's extensive experience in animal models, infectious diseases, immunology, metabolism, and gut microbiome research, drawing from her background at Cornell University, University of Georgia, and Cedars-Sinai Medical Center. Participate in live Q&A to deepen understanding of how these humanized mouse models are revolutionizing cell therapy research and immune modulator development.
