Cell-Cell and Cell-Substrate Adhesion Jointly Dictate Biofilm Morphogenesis

Explore how cell-cell and cell-substrate adhesion mechanisms work together to control biofilm morphogenesis in this 31-minute seminar presentation from the Biological Physics/Physical Biology seminar series. Discover the fundamental principles governing how bacterial cells organize themselves into complex three-dimensional biofilm structures through the interplay of different adhesion forces. Learn about the physical and biological factors that influence biofilm architecture, including the roles of cell-to-cell interactions and cell-surface attachment in determining final biofilm morphology. Gain insights into the quantitative approaches used to study these adhesion mechanisms and their implications for understanding bacterial community formation, antibiotic resistance, and biofilm-related infections in medical and industrial contexts.