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Explore the fascinating intersection of active matter physics and biological systems in this research seminar that examines how epithelial-mesenchymal transitions connect active matter theory, active solids mechanics, and cellular migration processes. Delve into the fundamental principles of active matter systems where individual components consume energy to generate motion and forces, and discover how these concepts apply to understanding complex biological phenomena. Learn about active solids as materials that can spontaneously deform and flow due to internal activity, and examine their role in biological contexts. Investigate the mechanisms of cell migration, focusing on how cells move through tissues and respond to mechanical and chemical cues. Understand epithelial-mesenchymal transitions (EMT) as crucial biological processes where epithelial cells lose their cell-cell adhesion properties and gain migratory and invasive characteristics, becoming mesenchymal cells. Discover how EMT serves as a unifying framework that encompasses principles from active matter physics, mechanics of active solids, and cellular migration dynamics. Gain insights into cutting-edge research that bridges theoretical physics and biological systems, revealing how physical principles can explain complex biological transformations essential for development, wound healing, and disease progression including cancer metastasis.
