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Join a 57-minute webinar led by Dr. Lisa K. Peterson, Associate Professor of Pathology at the University of Utah and Medical Director of Immunology at ARUP Laboratories, exploring the complexities of ribonucleoprotein (RNP) antibody testing in autoimmune diagnosis. Learn about the significance of RNP antibodies as serologic markers for mixed connective tissue disease (MCTD), understand the interaction between RNP and Smith (Sm) proteins, and examine various antigens and methods used for U1-RNP antibody detection. Discover the distinctions between systemic lupus erythematosus patients, who frequently have antibodies to both Sm and RNP, and MCTD patients, who only present RNP antibodies. Through case studies, explore challenges in result interpretation and improved nomenclature for reporting RNP antibodies. Gain valuable insights into the diverse solid-phase immunoassays used for RNP antibody detection and their implications for autoimmune diagnosis. PACE credits are available for registered Labroots members upon completion.
Syllabus
Is It Anti-RNP or Anti-Sm/RNP?
Taught by
Labroots