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Explore the potential effects of transmission-blocking drugs (TBDs) on malaria control and elimination through a mathematical modeling approach in this seminar by Dr. Woldegebriel Assefa Woldegerima from York University. Delve into the analysis of a proposed SEIRS-SEI type model that incorporates TBD treatment and protected human classes. Examine the impact of treatment coverage, drug efficacy, protective effects, and waning effects on malaria transmission dynamics. Learn about the model's validation using Python's "lmfit" library and its predictions under various scenarios. Gain insights into the mathematical and epidemiological implications of TBDs in reducing new malaria cases and mortality rates.
Syllabus
Investigating Transmission-Blocking Anti-malarial Drugs: A Mathematical Modelling Approach
Taught by
Fields Institute