High-Throughput Analysis of Pathogens Using Desorption Electrospray Ionization and 2D MS/MS

Learn advanced mass spectrometry techniques for rapid pathogen detection and characterization in this 33-minute webinar. Explore how desorption electrospray ionization (DESI) combined with two-dimensional tandem mass spectrometry (2D MS/MS) enables high-throughput analysis of biological threats including bacteria and viruses at sampling rates of approximately 300 samples per hour. Discover the integration of automated liquid handling robots with custom mass spectrometry platforms for streamlined biological sample processing. Compare the metabolomic and lipidomic capabilities of DESI-2D MS/MS systems against conventional LC-MS/MS benchtop systems operating at traditional sampling rates of 4 samples per hour. Examine applications for detecting and characterizing model biological organisms, determining medical countermeasure efficacy, and developing rapid analytical responses to emerging biological threats including COVID-19, resurgent vaccine-preventable diseases, and bacterial weaponry such as Bacillus anthracis. Understand the technological developments driving modern biological threat detection in response to 21st-century global crises and the need for rapid pathogen characterization and countermeasure development. Gain insights from Dr. Dalton T. Snyder's expertise in portable mass spectrometry for CBRNE detection and his experience developing surface-induced dissociation technology for native mass spectrometry applications.