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Learn advanced techniques for small molecule quantitation in a 54-minute webinar presented by mass spectrometry experts Courtney Patterson, MS, and Dr. Jingshu Guo. Explore the capabilities of the Thermo Scientific Stellar mass spectrometer for developing targeted quantitative workflows in clinical research. Master method development considerations for toxicology research, fast chromatography implementation, and automated intelligent instrument control. Discover how to enhance selectivity and specificity while achieving improved detection and quantitation limits using the instrument's quadrupole mass filter, dual-purpose ion concentrating routing multipole, and dual-pressure linear ion trap. Gain practical knowledge on leveraging higher energy dissociation (HCD) and resonant collisional dissociation (CID) using tMS2 and tMS3 acquisition for improved quantitative analysis in complex biological matrices. Focus on increasing productivity through streamlined method creation, creating targeted MS2 and MS3 methods in one analytical method, and understanding the benefits of Adaptive RT for scheduled PRM acquisition for small molecules.
