Driving Protein Research - Automated Liquid Handling and qPCR for Extraction and Thermal Analysis

Explore how automated liquid handling systems and qPCR technology can revolutionize protein research workflows in this 40-minute webinar presented by Jason Dexter and Matthias Ludwig. Discover how automation improves the reliability and robustness of protein characterization by streamlining protein purification and downstream thermal analysis processes. Learn about automated systems designed for small to medium volume samples that deliver high throughput and accurate results while eliminating the risks associated with time-consuming manual procedures. Understand how flexible liquid handling systems support efficient extraction and buffer exchange across various protein types, enabling reproducible sample preparation for downstream analysis. Examine affordable high-throughput tools for thermal profiling of proteins, including techniques for assessing stability and interactions, with particular emphasis on using qPCR systems for thermal shift assays that require minimal sample input while providing valuable insights into conformational changes and binding events. Compare qPCR as an alternative to traditional methods such as scanning fluorimetry or nanoDSF, highlighting its advantages in high throughput, low reagent consumption, and ease of use. Review practical examples demonstrating real-world applications of these technologies in protein research and biopharmaceutical development, whether for early-stage research or applied protein analytics, to help streamline critical workflow steps and ensure data confidence.