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YouTube

Early Innovative Combination Immunotherapy Trials for Colorectal Cancer Treatment

Dana-Farber Cancer Institute via YouTube

Overview

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Watch a 57-minute keynote presentation from Dr. Chalabi, a Gastrointestinal Oncologist and clinician scientist from the Netherlands Cancer Institute, as she discusses groundbreaking research on early innovative combination immunotherapy trials for colorectal cancer. Explore the evolution of immunotherapy, its mechanisms, and response determinants while learning about different types of colorectal cancer, including MMR proficient and MMR deficient cases. Gain insights into early-stage colon cancer treatment, the NICHE study design, treatment tolerance, and response evaluation. Understand the future prospects of immunotherapy for colorectal cancer and the goals researchers aim to achieve in this field. Delivered at the Young-Onset Colorectal Cancer Center's fourth annual Patient and Family Forum at Dana-Farber Cancer Institute, this comprehensive presentation combines clinical expertise with cutting-edge translational research to advance understanding of tumor response drivers and novel immunotherapy treatments.

Syllabus

Intro
History of immunotherapy
How does immunotherapy work?
What are the determinants of immunotherapy response?
Types of colorectal cancer MMR proficient versus MMR deficient
Early stage colon cancer: current situation
NICHE study design
Treatment tolerance
What does "response" look like?
The future of immunotherapy for CRC
What do we want to achieve?

Taught by

Dana-Farber Cancer Institute

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