Decoding the Tumor Microenvironment with Paletrra™: Revolutionizing Biomarker Discovery in Clinical Trials

Explore advanced tissue-based technology and spatial biology techniques in this webinar presented by Kirsteen Maclean, PhD and Harry Nunns. Discover how multi-omics technologies and comprehensive datasets enable the identification of disease biomarkers, particularly in oncology applications. Learn about the capabilities of the Paletrra™ end-to-end solution for generating whole-tissue data while maintaining enhanced histological context and conducting unbiased spatial analysis, specifically demonstrated in non-small cell lung cancer (NSCLC). Understand how spatial biology approaches using both RNA and protein analysis serve as powerful tools for characterizing and phenotyping cells within the tumor microenvironment. Examine the comprehensive spatial workflow that preserves tumor architectural features while revealing spatial relationships between tumor cells and immune cells. Focus on the characterization of specific cell phenotypes defined by co-localization of multiple proteins and RNA markers that may help predict clinical responses and identify mechanisms of resistance to therapy in clinical trials.