Emerging Methods to Study an Evolving Landscape: Characterizing the Tumor Microenvironment with Spatial Biology

Explore advanced spatial biology approaches for characterizing the tumor microenvironment (TME) in this 53-minute webinar presented by Dr. Andrea Radtke, a Principal Scientist at Leica Microsystems and co-developer of the IBEX multiplexed antibody-based imaging method. Gain comprehensive insights into various spatial biology methodologies, their technical capabilities, and crucial study design considerations for cancer research. Learn about integrating multiple single cell and spatial methods to build multi-omic atlases of normal and malignant tissues, with a specific focus on follicular lymphoma (FL). Understand how FL malignant B cells modify the lymphoid environment by altering other cells' phenotype, distribution, and abundance. Master the benefits and challenges of multi-omic studies, discover community resources for multiplexed imaging, and evaluate key factors in selecting appropriate spatial biology platforms based on study size, analyte number, resolution requirements, and tissue imaging area.